11Beta-hydroxysteroid dehydrogenase type 2 deficiency also known as (11beta-HSD2) is one of the most common causes of retention of sodium and serious cases of hypertension. This happens when glucocorticoids are admitted to the mineralocorticosteroid receptors which are non-selective.
To properly prescribe a specific treatment or therapy to patients that are deficient in 11 beta-hydroxysteroid dehydrogenase type 2 genes, it is important that AME diagnosis be done accurately.